Recent progress on nanovehicles.

نویسندگان

  • Yasuhiro Shirai
  • Jean-François Morin
  • Takashi Sasaki
  • Jason M Guerrero
  • James M Tour
چکیده

Nanovehicles are a new class of molecular machines consisting of a molecular scale chassis, axles, and wheels, that can roll across solid surfaces with structurally defined directions making them of interest to synthetic chemists, surface scientists, chemical engineers, and the general car enthusiast. In this tutorial review, following a brief introduction to the development of nanomachines, our recent progress on the nanovehicle project is presented including the design, synthesis, and testing of a series of nanocars, nanotrucks, and motorized nanocars.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A facile synthesis of strong near infrared fluorescent layered double hydroxide nanovehicles with an anticancer drug for tumor optical imaging and therapy.

In this work, a new multifunctional nanovehicle for tumor optical imaging and therapy was developed using Y2O3:Er(3+),Yb(3+) nanoparticles as near infrared fluorescent nanophosphors, and MgAl-layered double hydroxide (LDH) nanosheets as anticancer drug nanovehicles. Monodispersed Y2O3:Er(3+),Yb(3+) nanophosphors were readily synthesized by the urea assisted homogenous precipitation method. Hier...

متن کامل

Nanocarriers for siRNA Therapy

Small interfering RNAs (siRNAs) therapy has opened exceptional advantageous opportunity for the treatment of diseases. Usually naked siRNA are subjected to internal harsh environment and rapidly degraded by RNases after administration. To overcome this issue various nanodelivery platforms have been developed and utilized in drug delivery due to narrowed size distribution, improved bioavailabili...

متن کامل

From the Synthesis of Nanovehicles to Participation in the First Nanocar Race-View from the French Team.

This review article presents our accomplished work on the synthesis of molecular triptycene wheels and their introduction into nanovehicles such as wheelbarrows and nanocars, equipped with two and four wheels, respectively. The architecture of nanovehicles is based on polycyclic aromatic hydrocarbons, which provide a potential cargo zone. Our strategy allowed us to obtain planar or curved nanoc...

متن کامل

Peptide-mediated core/satellite/shell multifunctional nanovehicles for precise imaging of cathepsin B activity and dual-enzyme controlled drug release

Intracellular imaging of pathologically relevant proteases can provide essential information for the accurate evaluation of disease stage and progression. However, the risks of degradation by nonspecific enzymes during transportation and poor cellular uptake limit the use of peptide-based molecular probes (PMPs) for in situ protease imaging. To overcome these obstacles, a self-protected nanoveh...

متن کامل

β-casein nanovehicles for oral delivery of chemotherapeutic drug combinations overcoming P-glycoprotein-mediated multidrug resistance in human gastric cancer cells

Multidrug resistance (MDR) is a primary obstacle to curative cancer therapy. We have previously demonstrated that β-casein (β-CN) micelles (β-CM) can serve as nanovehicles for oral delivery and target-activated release of hydrophobic drugs in the stomach. Herein we introduce a novel nanosystem based on β-CM, to orally deliver a synergistic combination of a chemotherapeutic drug (Paclitaxel) and...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Chemical Society reviews

دوره 35 11  شماره 

صفحات  -

تاریخ انتشار 2006